Signature Science, LLC
  • - TX-Austin
  • Austin, TX, USA
  • Full Time

Position Purpose:   

To design, develop, evaluate and modify computer programs to process, manage, and analyze DNA sequencing and/or chemometrics data sets. The Data Science Programmer is responsible for identifying and resolving program or data issues, writing well-documented computer code, and validating computer programs.  


Essential Duties and Responsibilities:

  • Develop tools for management, analysis and interpretation of sequence data, molecular biology analytical data, and/or chemical analysis data
  • Implement and execute data processing workflows and automated analytic pipelines
  • Create standardized summary tables and figures
  • Manage large dataset collections including analytical results and data QC
  • Write well-documented computer code and conduct code reviews and programming validation
  • Conduct workflow benchmarking
  • Identify inconsistencies and initiate resolution of data problems
  • Prepare SOPs, document source code/workflows, and write reports to summarize computational
    requirements, processing status, and customized analysis results as needed.


Required Knowledge, Skills & Abilities:


  • Demonstrated computer programming skills in Perl and/or Python as well as R for statistical programming
  • Ability to develop and query relational databases (MySQL or similar)
  • Familiarity with next-generation sequencing data and open-source bioinformatics tools desired
  • Familiarity with AWS cloud computing is desired
  • Experience with NextFlow, SnakeMake, or similar workflow/pipeline management systems is desired
  • Experience using Version Control software (e.g., Git or similar) to manage programming code
  • Experience using workflows and sprints throughout the development process
  • Competent in using Linux/Unix operating system command line interface
  • Ability to manage multiple tasks
  • Ability to work independently, as well as in a team environment
  • Ability to effectively communicate technical concepts, both written and oral
  • Proactive, self-starter




  • Bachelor's degree in Bioinformatics, Computer Science, or a related field
  • 3-5 years of relevant experience



Certificates and Licenses:




This position requires that the candidate be willing and able to complete a successful background screening for a security clearance. Candidates with an active security clearance will receive preference.


Supervisory Responsibilities:


May serve as a task/project lead. Must be willing to collaborate


Working Conditions/ Equipment:

  • Ability to work in varying conditions to include: traditional office environments with sedentary extended periods required for code development and testing;


The above job description is not intended to be an all-inclusive list of duties and standards of the position.  Incumbents will follow any other instructions, and perform any other related duties, as assigned by their supervisor.



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